The TRUFFLE group (Trial of Umbilical and Fetal Flow in Europe) was founded in 2002 following meetings in Cambridge and Turin. The group then planned and conducted a prospective multicentre randomized management study of fetal growth restriction, performed in 20 European major perinatal centres in 7 countries between 2005 and 2010.

The TRUFFLE study founding members are Gerry Visser, Katia Bilardo, Tullia Todros, Christoph Lees, Hans Wolf, Tiziana Frusca, Kurt Hecher, Bine Arabin, Hans Duvekot, Christoph Brezinka, Enrico Ferrazzi and Gerald Albaiges but quickly enlarged to include experts throughout the UK and Europe.

The group is co-ordinated by Professor Christoph Lees at Imperial College London. Data management is by Dr Hans Wolf, Amsterdam, NL and neonatal/paediatric follow up by Professor Neil Marlow (London) and Dr Aleid van Wassenaer (Amsterdam).

The Data monitoring committee of the TRUFFLE 1 study were Jim Thornton (Nottingham), Chair; Herbert Valensise (Rome), Karel Marsal (Lund) and John Kingdom (Toronto).